mitotic spindle

CELL BIOLOGY: ON THE ORCHESTRATION OF THE MITOTIC SPINDLE: "Mitotic spindle, a precision machine made from a bipolar array of microtubules that are focused at each end of the spindle by a centrosome or spindle pole body. Microtubules are themselves dynamic polymers that interact with chromosomes in the middle of the spindle and provide tracks to separate them toward the poles. Without the spindle, cell division would be impossible, and subtle defects in its function are likely to be involved with the genomic instability associated with cancer."