Wednesday, December 13, 2006

receptor-mediated endocytosis

Receptor-mediated endocytosis creates receptosomes. Cells invaginate proteins and other types of ligands that have attached to specific receptors on the plasma membrane. First, the protein or ligand binds to a specific receptor, forming a coated pit ("coated pit endocytosis"). The coated pit is a specialized membranous region coated with clathrin, which provides stability and aids the transport process. Next, the coated pit next forms a coated vesicle and, shedding its clathrin coat, joins with other coated pits to form a receptosome.

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